Science is plagued by incidents of fraud. Although fraud is clearly wrong, many other actions that researchers engage in do not represent fraud. Yet one may question the ethical integrity of these actions. We probably make many decisions in doing research unaware of their ethical ramifications. This symposium deals with “Sloppy Science” as a grey area of ethical research conduct. What is sloppy science? What is acceptable and what not? Can we prevent sloppy science? How can we do that? A forum of experienced researchers discusses these questions with the audience at the AMEE meeting in 2014.